羟基积雪草甙 × 抗皱

研究使用5%维生素C和0.1%羟基积雪草苷复方，无法单独归因于羟基积雪草苷，且仅三分之二受试者改善。

The study used a combination of 5% vitamin C and 0.1% madecassoside, so the anti-wrinkle efficacy cannot be solely attributed to madecassoside, and only two-thirds of subjects improved.

摘要显示CANP促进成纤维细胞增殖和胶原产生，但抗皱功效未直接评估，且为复合物。

The abstract shows that CANP promotes fibroblast proliferation and collagen production, but anti-wrinkle efficacy was not directly assessed, and it is a complex.

摘要显示羟基积雪草苷预处理可抑制UVB诱导的MMP生成并增加细胞内胶原水平，但未直接测量抗皱功效。

The abstract shows that madecassoside pretreatment inhibits UVB-induced MMP production and increases intracellular collagen levels, but did not directly measure anti-wrinkle efficacy.

摘要仅涉及羟基积雪草苷的控释，未评估抗皱功效。

The abstract only involves controlled release of madecassoside, without assessing anti-wrinkle efficacy.

摘要显示积雪草提取物在50 mg/mL时促进胶原合成，但未单独测试羟基积雪草苷的抗皱功效，且未涉及人体或动物抗皱终点。

The abstract shows that Centella asiatica extract promotes collagen synthesis at 50 mg/mL, but did not separately test the anti-wrinkle efficacy of madecassoside, and does not involve human or animal anti-wrinkle endpoints.

摘要为积雪草苷等化合物的综述，未提供抗皱功效的直接证据。

The abstract is a review of compounds such as asiaticoside, without providing direct evidence of anti-wrinkle efficacy.

摘要提及羟基积雪草苷通过促进成纤维细胞增殖和胶原合成等机制，但未提供直接抗皱功效证据。

The abstract mentions that madecassoside promotes fibroblast proliferation and collagen synthesis, but does not provide direct evidence of anti-wrinkle efficacy.