金盏花（CALENDULA OFFICINALIS）提取物 × 舒缓

大鼠伤口愈合实验显示促进胶原合成和再上皮化，支持舒缓修复功效

Rat wound healing experiment shows promotion of collagen synthesis and re-epithelialization, supporting soothing repair efficacy.

5%和10%金盏花凝胶显著降低口腔黏膜炎评分，加速愈合，支持舒缓功效

5% and 10% calendula gel significantly reduced oral mucositis scores and accelerated healing, supporting soothing efficacy

凝胶含多种活性成分，无法单独归因于金盏花；虽改善症状，但混杂因素多

Gel contained multiple active ingredients, cannot be solely attributed to calendula; although symptoms improved, there were many confounding factors

显示皮肤水合和紧致度改善，但未直接评估舒缓功效，且部分参数不显著

Showed improvement in skin hydration and firmness, but did not directly assess soothing efficacy, and some parameters were not significant

局部凝胶维持GSH水平并减少组织学改变，但未影响MMP-9和MPO，舒缓功效部分支持

Topical gel maintained GSH levels and reduced histological changes, but did not affect MMP-9 and MPO; soothing efficacy partially supported

口服给药，非局部；虽显示抗氧化和MMP调节，但非直接舒缓功效，且需进一步研究

Oral administration, not topical; although shows antioxidant and MMP regulation, it is not direct soothing efficacy and requires further study.

仅评估了抗氧化和抗菌活性，未直接测试舒缓功效

Only evaluated antioxidant and antibacterial activities, not directly tested soothing efficacy

仅评估了成纤维细胞增殖和抗菌性，未直接测试舒缓功效

Only evaluated fibroblast proliferation and antibacterial activity, without directly testing soothing efficacy.