甘草酸二钾

有文献报告，在1049名芬兰女性中，母亲摄入甘草酸>500 mg/周与婴儿早产（<38周）相关，但出生体重和血压无关联；动物实验显示无生殖发育毒性，仅在大鼠高剂量下出现胸骨变异。暴露途径为口服，非外用。

Literature reports that in 1049 Finnish women, maternal consumption of glycyrrhizic acid >500 mg/week was associated with preterm birth (<38 weeks), but no association with birth weight or blood pressure; animal studies showed no reproductive/developmental toxicity except for sternebral variants at high doses in rats. Exposure route is oral, not topical.