壳多糖

QCOD@Sal无皮肤刺激，且促进皮肤修复

QCOD@Sal showed no skin irritation and promoted skin repair

体内试验显示敷料无皮肤刺激或致敏作用

In vivo tests showed no skin irritation or sensitisation effects

壳聚糖（甲壳素衍生物）水凝胶在体内角膜伤口愈合中显示最小炎症，且体外细胞存活率>95%，表明无眼刺激。

Chitosan (chitin derivative) hydrogels showed minimal inflammation in vivo corneal wound healing and >95% cell viability in vitro, indicating no eye irritation.

离体猪角膜研究显示甲壳素纳米凝胶无破坏或炎症迹象，表明无眼刺激。

Ex vivo porcine cornea study showed no signs of destruction or inflammation, indicating no eye irritation.

该文献通过动物试验证实甲壳素二己酸酯和甲壳素二丁酸酯对皮肤无致敏性和刺激性，即无致敏风险。

The study demonstrated that chitin dihexanoate and chitin dibutyrate are non-allergic and non-irritating to skin in animal tests, indicating no sensitization risk.

该文献研究的是氟芬隆（一种甲壳素合成抑制剂）对昆虫的生殖毒性，甲壳素仅作为背景提及，并非测试成分，且研究物种为昆虫，与人体孕期安全性无关。

This study investigates reproductive toxicity of flufenoxuron (a chitin synthesis inhibitor) on insects; chitin is only mentioned as background, not as a test substance, and the species is insect, irrelevant to human pregnancy safety.

该文献研究的是乙螨唑（一种甲壳素合成抑制剂）对斑马鱼的发育毒性，甲壳素仅作为背景提及，并非测试成分，且研究物种为鱼类，与人体孕期安全性无关。

This study investigates developmental toxicity of etoxazole (a chitin synthesis inhibitor) on zebrafish; chitin is only mentioned as background, not as a test substance, and the species is fish, irrelevant to human pregnancy safety.

该文献研究的是聚苯乙烯纳米颗粒对贻贝胚胎的发育毒性，甲壳素仅作为壳形成相关基因被检测，并非测试成分，且研究物种为海洋无脊椎动物，与人体孕期安全性无关。

This study investigates developmental toxicity of polystyrene nanoparticles on mussel embryos; chitin is only mentioned as a gene involved in shell formation, not as a test substance, and the species is marine invertebrate, irrelevant to human pregnancy safety.

羟丙基甲壳素作为微针基质用于经皮递送罗哌卡因和右美托咪定，未报道甲壳素本身引起经皮渗透风险或皮肤刺激；研究强调绿色工艺避免安全问题，但未具体研究甲壳素的安全终点。

Hydroxypropyl chitin used as microneedle matrix for transdermal delivery of ropivacaine and dexmedetomidine; no report of chitin itself causing percutaneous penetration risk or skin irritation; study emphasizes green process to avoid safety concerns but does not specifically investigate chitin safety endpoint.

羟丙基甲壳素作为微针基质，用于经皮递送吡罗昔康，未报道甲壳素本身引起经皮渗透风险或皮肤刺激；研究关注药物递送和抗炎效果，未提及甲壳素的安全性问题。

Hydroxypropyl chitin used as microneedle matrix for transdermal piroxicam delivery; no report of chitin itself causing percutaneous penetration risk or skin irritation; study focuses on drug delivery and anti-inflammatory efficacy, not chitin safety.