The study investigates NAC eye drops for cataract treatment, does not mention eye irritation, and describes it as safe.
脂质过氧化与白内障：N-乙酰肌肽作为治疗人类和犬类年龄相关性白内障的工具
结论解读 · 中文
文献研究N-乙酰肌肽滴眼液治疗白内障，未提及眼刺激，且描述为安全有效，故不支持眼刺激风险
结论解读 · EN
The study investigates N-acetylcarnosine eye drops for cataract treatment, does not mention eye irritation, and describes it as safe and effective, thus does not support eye irritation risk.
天然含组氨酸二肽Nα-乙酰肌苷作为眼科用抗氧化剂
结论解读 · 中文
兔眼给予1% NAC后显示良好耐受性，未报告眼刺激
结论解读 · EN
Rabbit eyes treated with 1% NAC showed excellent toleration, no eye irritation reported.
Nα-乙酰肌肽是L-肌肽在眼科应用中的前药，作为抗氧化剂
结论解读 · 中文
兔眼给予1% NAC后显示良好耐受性，未报告眼刺激
结论解读 · EN
Rabbit eyes treated with 1% NAC showed excellent toleration, no eye irritation reported.
02
生殖毒性与孕期使用
2 条
公开文献2
肌肽和组氨酸补充通过抗氧化和线粒体依赖性机制减轻铅诱导的生殖毒性
结论解读 · 中文
系统性暴露证据（口服），且肌肽作为保护剂而非毒性诱导剂，未直接证实肌肽本身的生殖毒性
结论解读 · EN
Systemic exposure evidence (oral), and carnosine was used as a protective agent against lead toxicity, not directly demonstrating its own reproductive toxicity.
Carnosine was one of the control antioxidants, active only at ≥10⁻⁴ M, and no specific developmental toxicity was reported for carnosine; main toxicity was from L-methionine.
03
经皮渗透
2 篇 · 结论均为原作者观点
共递送羟基频哪酮视黄酸酯和肌肽的纳米脂质体平台用于增强表皮/真皮递送和多效抗衰老功效
结论解读 · 中文
该文献研究肌肽的递送和抗衰老功效，未涉及经皮渗透安全风险，且结果显示制剂生物相容性好，无细胞毒性。
结论解读 · EN
This study focuses on delivery and anti-aging efficacy of carnosine, not percutaneous penetration safety; results show good biocompatibility without cytotoxicity.
This study investigates the anti-photoaging efficacy of carnosine, not its percutaneous penetration safety risk; results show the formulation is safe and effective without evidence of irritation or sensitization.