神经酰胺 NP × 修护

含Cer NP的脂质混合物显著改善皮质类固醇损伤的皮肤屏障功能，包括屏障恢复率、水合等，且Cer NP水平升高。

A lipid mixture containing Cer NP significantly improves skin barrier function impaired by topical corticosteroids, including barrier recovery rate, hydration, etc., and Cer NP levels increase.

番茄籽皂苷（含lycoperoside H）在HaCaT细胞和重建表皮模型中上调丝聚蛋白、神经酰胺合成酶，增加Cer NP含量，降低TEWL。

Tomato seed saponin (containing lycoperoside H) upregulates filaggrin and ceramide synthase in HaCaT cells and reconstructed epidermis, increases Cer NP content, and reduces TEWL.

综述指出Cer NP与皮肤干燥的关联不一致，部分研究支持，部分不支持，证据异质性高。

The review indicates inconsistent association between Cer NP and dry skin, with some studies supporting and others not, high heterogeneity of evidence.

研究显示AD患者非皮损处Cer NP/NS比值与健康人有差异，且与皮肤屏障参数相关，但未直接测试CERAMIDE NP的修护功效，仅为相关性分析。

The study shows that the Cer NP/NS ratio in non-lesional skin of AD patients differs from healthy controls and correlates with skin barrier parameters, but does not directly test the repair efficacy of CERAMIDE NP, only correlation analysis.

测试的润肤剂含5%尿素、Cer NP和乳酸，结果显示改善皮肤水合和屏障功能，但无法区分Cer NP的单独贡献，因产品为复合配方。

The tested emollient contains 5% urea, Cer NP, and lactic acid, showing improved skin hydration and barrier function, but cannot distinguish the individual contribution of Cer NP due to the composite formulation.

仅开发了检测外源性Cer NP的方法，未测试其修护功效。

Only develops a method to detect exogenous Cer NP, without testing its repair efficacy.

研究Cer NP在脂质模型中的相行为和组织结构，未涉及修护功效。

Studies the phase behavior and organization of Cer NP in lipid models, without involving repair efficacy.

仅通过模拟研究Cer NP的分子结构及氢键网络，未涉及修护功效的生物学验证。

Only simulates the molecular structure and hydrogen bonding network of Cer NP, without involving biological validation of repair efficacy.